MICROCEL® MC-12
Microcrystalline Cellulose
Product Profile

MICROCEL® MC-12
Microcrystalline Cellulose

 

Product Name MICROCEL® MC-12
Generic Name Microcrystalline Cellulose
Physico-chemical properties
Compliance EP/USP-NF
Synonyms Cellulose, Microcrystalline
CAS Number 9004-34-6
Chemical Structure
Physical Form or Appearence White, non-fibrous powder
Application MICROCEL® MC-12 microcrystalline cellulose is a filler/binder and fiber source for pharmaceutical oral dosage and nutraceutical forms. It has optimized compactibility and flow properties and is primarily used in direct compression.
Water content (LOD)

Water Content (LOD) Maximum: 7 %

Morphology
Average mean particle diameter 160 µm
Particle Size Distribution by Laser Diffraction

dv10: 60 µm

dv50: 180 µm

dv90: 380 µm

Solubility Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents
Water sorption isotherm at 20°C
Taste/Odor Odorless and tasteless
Tablet hardness
Experimental Conditions for Compression Behavior

Tablet Press: STYLCAM 200R

Production Speed: 10, 25 and 40 tablets/min (respective linear punch velocity: 38, 96 and 152 mm/s ; respective simulated rotary press speed: 60000, 150000 and 250000 tablets/hour)

Tooling: Diameter 10 mm flat

Formula: 100% MICROCEL® MC-12

Tablet Mass: 400 mg

Powder Characteristics

Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): 16 s

Bulk Density: 0.37 g/cm3

Tapped Density: 0.53 g/cm3

True Density: 1.54 g/cm3

Specific surface area: 1.05 m2/g

Angle of Repose: 36 °

 

Disclaimer

These typical values are provided for information only and we believe them to be reliable. Methods available upon request.

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