Product Profile
MICROCEL® MC-112
Microcrystalline Cellulose
| Product Name | MICROCEL® MC-112 |
| Generic Name | Microcrystalline Cellulose |
| Physico-chemical properties | |
| Compliance | EP/USP-NF |
| Synonyms | Cellulose, Microcrystalline |
| CAS Number | 9004-34-6 |
| Chemical Structure |
|
| Physical Form or Appearence | White, non-fibrous powder |
| Application | MICROCEL® MC-112 microcrystalline cellulose is a low moisture content direct compression excipient and fiber source for pharmaceutical oral dosage and nutraceutical forms. It is also suitable for dry granulation. |
| Water content (LOD) |
Water Content (LOD) Maximum: 1.5 % |
| Morphology |
|
| Average mean particle diameter | 100 µm |
| Particle Size Distribution by Laser Diffraction |
dv10: 38.4 µm dv50: 100 µm dv90: 235 µm |
| Solubility | Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents |
| Water sorption isotherm at 20°C |
|
| Taste/Odor | Odorless and tasteless |
| Tablet hardness |
|
| Experimental Conditions for Compression Behavior |
Tablet Press: STYLCAM 200R Production Speed: 10, 25 and 40 tablets/min (respective linear punch velocity: 38, 96 and 152 mm/s ; respective simulated rotary press speed: 60000, 150000 and 250000 tablets/hour) Tooling: Diameter 10 mm flat Formula: 99.9% MICROCEL® MC-112 / 0.1% Fumed silica Tablet Mass: 400 mg |
| Powder Characteristics |
Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): Not free-flowing Bulk Density: 0.38 g/cm3 Tapped Density: 0.54 g/cm3 True Density: 1.54 g/cm3 Angle of Repose: 37 ° |
Â
Disclaimer
These typical values are provided for information only and we believe them to be reliable. Methods available upon request.