Product Profile
MICROCEL® 301 SD
Microcrystalline Cellulose
| Product Name | MICROCEL® 301 SD |
| Generic Name | Microcrystalline Cellulose |
| Physico-chemical properties | |
| Compliance | EP/USP-NF/JP |
| Synonyms | Cellulose, Microcrystalline |
| CAS Number | 9004-34-6 |
| Chemical Structure |
|
| Physical Form or Appearence | White, non-fibrous powder |
| Application | MICROCEL® 301 SD microcrystalline cellulose is a direct compression excipient for pharmaceutical oral dosage and nutraceutical forms (fiber source). It is also suitable for dry granulation. MICROCEL® 302 SD is a spray-dried product from EXCiPACTâ„¢ (International Pharmaceutical Excipients Certification) certified plant. |
| Water content (LOD) |
Water Content (LOD) Maximum: 5 % |
| Morphology |
|
| Average mean particle diameter | 50 µm |
| Particle Size Distribution by Laser Diffraction |
dv10: 16 µm dv50: 55 µm dv90: 135 µm |
| Solubility | Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents |
| Water sorption isotherm at 20°C |
|
| Taste/Odor | Odorless and tasteless |
| Tablet hardness |
|
| Experimental Conditions for Compression Behavior |
Tablet Press: STYLCAM 200R Production Speed: 10 and 40 tablets/min (respective linear punch velocity: 38 and 152 mm/s; respective simulated rotary press speed: 60000 and 250000 tablets/hour) Tooling: Diameter 10 mm flat Formula: 100% MICROCEL® 301 SD Tablet Mass: 400 mg |
| Powder Characteristics |
Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): Not free-flowing Bulk Density: 0.42 g/cm3 Tapped Density: 0.64 g/cm3 True Density: 1.54 g/cm3 Specific surface area: 1.01 m2/g Angle of Repose: 36 ° |
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Disclaimer
These typical values are provided for information only and we believe them to be reliable. Methods available upon request.