MICROCEL® 301 SD
Microcrystalline Cellulose
| Product Name | MICROCEL® 301 SD |
| Generic Name | Microcrystalline Cellulose |
| Physico-chemical properties | |
| Compliance | EP/USP-NF/JP/CHP |
| Synonyms | Cellulose, Microcrystalline |
| CAS Number | 9004-34-6 |
| Chemical Structure |
|
| Physical Form or Appearence | White, non-fibrous powder |
| Application | MICROCEL® 301 SD microcrystalline cellulose is a direct compression excipient for pharmaceutical oral dosage and nutraceutical forms (fiber source). It is also suitable for dry granulation. MICROCEL® 301 SD is a spray-dried product from EXCiPACT™ (International Pharmaceutical Excipients Certification) certified plant. |
| Water content (LOD) |
Water Content (LOD) Maximum: 5 % |
| Morphology |
|
| Average mean particle diameter | 50 µm |
| Particle Size Distribution by Laser Diffraction |
dv10: 16 µm dv50: 55 µm dv90: 135 µm |
| Solubility | Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents |
| Water sorption isotherm at 20°C |
|
| Taste/Odor | Odorless and tasteless |
| Tablet hardness |
|
| Experimental Conditions for Compression Behavior |
Tablet Press: STYLCAM 200R Production Speed: 10 and 40 tablets/min (respective linear punch velocity: 38 and 152 mm/s; respective simulated rotary press speed: 60000 and 250000 tablets/hour) Tooling: Diameter 10 mm flat Formula: 100% MICROCEL® 301 SD Tablet Mass: 400 mg |
| Powder Characteristics |
Powder Flowability (according to Ph.Eur. 2.9.16, 10mm outflow opening): Not free-flowing Bulk Density: 0.4 g/cm3 Tapped Density: 0.64 g/cm3 True Density: 1.54 g/cm3 Specific surface area: 1.01 m2/g Angle of Repose: 36 ° |
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® Registered trademark(s) of Roquette Frères. Any information provided herein is intended for healthcare and food industry professionals for internal use only and not to be delivered as such to final consumers. Information is based on our current state of knowledge and made available on an informational basis; products described may have restrictions with respect to their use, communication, and/or usage levels, and such may vary on a country-by-country basis. Manufacturers of dietary supplements should evaluate the intended use of the particular ingredient in their finished dietary supplement to confirm compliance with the applicable laws and regulations of authorities regulating such products, because the suitability and regulatory status of a product may be dependent on its specific intended use. As the use of these products is beyond our control, Roquette makes no express or implied warranties regarding the use of the product and no guarantee of product properties, and in particular no express or implied warranties regarding the use of the product in dietary supplements, including without limitation the implied warranties of merchantability and fitness for a particular purpose, and Roquette disclaims liability for any loss and/or damage related to such use. Roquette, further, does not warrant that the information or its use will not infringe any patent or other proprietary rights of any third party. Roquette providing this information is not a commitment to sell any product encompassing any of such information in the future.