MICROCEL® 101 SD
Microcrystalline Cellulose
Product Profile

MICROCEL® 101 SD
Microcrystalline Cellulose

Product Name MICROCEL® 101 SD
Generic Name Microcrystalline Cellulose
Physico-chemical properties
Compliance EP/USP-NF/JP
Synonyms Cellulose, Microcrystalline
CAS Number 9004-34-6
Chemical Structure
Physical Form or Appearence White, non-fibrous powder
Application MICROCEL® 101 SD microcrystalline cellulose is a filler/binder and fiber source for pharmaceutical oral dosage and nutraceutical forms. It has optimized compactibility and is primarily used in wet granulation. MICROCEL® 101 SD is a spray-dried product from EXCiPACT™ (International Pharmaceutical Excipients Certification) certified plant.
Water content (LOD)

Water Content (LOD) Maximum: 5 %

Morphology
Average mean particle diameter 50 µm
Particle Size Distribution by Laser Diffraction

dv10: 17 µm

dv50: 59 µm

dv90: 139 µm

Solubility Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents
Water sorption isotherm at 20°C
Taste/Odor Odorless and tasteless
Tablet hardness
Experimental Conditions for Compression Behavior

Tablet Press: STYLCAM 200R

Production Speed: 10 and 40 tablets/min (respective linear punch velocity: 38 and 152 mm/s; respective simulated rotary press speed: 60000 and 250000 tablets/hour)

Tooling: Diameter 10 mm flat

Formula: 100% MICROCEL® 101 SD

Tablet Mass: 400 mg

Powder Characteristics

Powder Flowability (according to Ph.Eur. 2.9.16, 25mm outflow opening): 10 s

Bulk Density: 0.32 g/cm3

Tapped Density: 0.47 g/cm3

True Density: 1.54 g/cm3

Specific surface area: 1.29 m2/g

Angle of Repose: 42 °

 

Disclaimer

These typical values are provided for information only and we believe them to be reliable. Methods available upon request.

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