Sugar-free Antacid Chewable Tablets Using PEARLITOL® 200 SD Mannitol
Formulation Guideline

Sugar-free Antacid Chewable Tablets Using PEARLITOL® 200 SD Mannitol

Directly compressible formulation for sugar-free antacid chewable tablets

Formula
% (by weight)
mg / tablet
PEARLITOL® 200 SD mannitol
71.7
573.6
Aluminium hydroxide
20.0
160.0
Magnesium hydroxide
5.0
40.0
Magnesium stearate
2.0
16.0
Buttermint flavor
1.0
8.0
AEROSIL® R972 silica*
0.3
2.4

Method

  1. Mix aluminium hydroxide, magnesium hydroxide and silica in the mixer for 5 minutes.
  2. Add the flavor and PEARLITOL® 200 SD and mix again for 5 minutes.
  3. Add the magnesium stearate and mix for 5 minutes.
  4. Compress the powder with 13 mm round flat face punches.

Additional comments

  • Tablet weight: 800 mg
  • Tablet thickness: 4.40 mm 
  • Tablet density: 1.373 g/cm3
  • Tablet hardness: 80 N

Disclaimer

This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s). 
These details are for information only and we believe them to be reliable.

*AEROSIL®R972 is registered trademark of Evonik 

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