Formulation Guideline
Placebo Hard Chewable Tablets Using PEARLITOL® 200 SD Mannitol and XYLISORB® 300 Xylitol
Directly compressible formulation for placebo hard chewable tablets
Formula
|
% (By weight) |
mg / tablet |
---|---|---|
PEARLITOL® 200 SD mannitol |
72.687 |
1046.7 |
XYLISORB® 300 xylitol |
24.250 |
349.2 |
Red berry flavor (Mane) |
1.000 |
14.4 |
Dualake FDC Red N°40 HD (Sensient) |
0.060 |
0.86 |
Eurolake Patent blue V (Sensient) |
0.003 |
0.04 |
Magnesium stearate |
2.000 |
28.8 |
 Method
- In a mixer, mix PEARLITOL® 200 SD, XYLISORB® 300, flavor and colors for 5 minutes.
- Add magnesium stearate and mix for 5 minutes.
- Compress the powder with 18 mm flat face bevel edge punches.
Additional comments
- Tablet weight: 1440 mg
- Tablet thickness: 4.7 mm
- Tablet density: 1.211 g/cm3
- Â Tablet hardness: 106 N
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).Â
These details are for information only and we believe them to be reliable.