Formulation Guideline
Placebo Chewable Tablets with PEARLITOL® 200 SD Mannitol
Directly compressible formulation for placebo chewable tablets
Formula
|
% (by weight)
|
mg / tablet
|
---|---|---|
PEARLITOL 200 SD mannitol
|
97.50
|
975.0
|
Caramel flavor
|
0.50
|
5.0
|
Vanilla flavor
|
0.50
|
5.0
|
Magnesium stearate (Barlocher)
|
1.50
|
15.0
|
Method
- In a mixer, mix PEARLITOL® 200 SD and the flavors for 5 minutes.
- Add magnesium stearate and mix for another 5 minutes.
- Compress the powder with 16 mm flat face bevel edge punches.
Additional Comments
- Tablet weight: 1000 mg
- Tablet thickness: 4.5 mm
- Tablet density: 1.103 g/cm3
- Â Tablet hardness: 80 N
Disclaimer
This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s).Â
These details are for information only and we believe them to be reliable.