Ginseng swallowable tablet formulation for direct compression
Formulation Guideline

Ginseng swallowable tablet formulation for direct compression

Directly compressible formulation of ginseng oral tablets using StarLac® co-processed lactose starch as filler-binder with disintegrant properties

Objective

Develop a prototype formulation for oral tablets of ginseng demonstrating the desirable flow and tabletability of StarLac® as a filler-binder with disintegrant properties for direct compression process.

Formula

Ingredient

Functionality of the ingredient

mg/tablet
(total weight: 670 mg)

% by weight

Ginseng powder

Active ingredient

67.0

10.0

StarLac® co-processed lactose starch

Direct compression filler-binder and disintegrant

599.7

89.5

Magnesium stearate

Lubricant

3.3

0.5

Method

1. In a mixer, mix StarLac® co-processed lactose starch with the ginseng powder for 5 minutes.
2. Add the magnesium stearate and mix for 5 minutes more.
3. Compress the powder with a 13 mm diameter concave punch.

Additional comments

Tablet hardness

131 N

Tablet density 

1.364 g/cm3

Tablet thickness

5.45 mm

Tablet mass

670 mg

Comment on Roquette product benefits

StarLac® co-processed lactose starch is a filler/binder having strong disintegrant properties. The co-processing offers superior benefit compared to a blend of lactose and starch, which allows you to improve the performance (hardness, friability, disintegration time) of your existing formulation. Specifically designed for direct compression applications, StarLac® is also an excellent filler/binder in dry granulation processes. StarLac® can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications including granules, swallowable tablets, orally dispersible tablets and hard capsules.

StarLac® is EP/USP-NF compliant.

 

StarLac® is a product co-marketed by Meggle and Roquette. StarLac® is a registered trademark of Meggle AG.

Disclaimer

This formula is a guideline for recommended use of our products; it does not imply consent to their use in violation of existing patent(s). 
These details are for information only, and we believe them to be reliable.

 

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